cyu@sh.itjust.works to Technology@lemmy.worldEnglish · 2 years agoNew Vaccine Targets Alzheimer’s Disease at its Roots - Neuroscience Newsneurosciencenews.comexternal-linkmessage-square17fedilinkarrow-up1268arrow-down12cross-posted to: [email protected]
arrow-up1266arrow-down1external-linkNew Vaccine Targets Alzheimer’s Disease at its Roots - Neuroscience Newsneurosciencenews.comcyu@sh.itjust.works to Technology@lemmy.worldEnglish · 2 years agomessage-square17fedilinkcross-posted to: [email protected]
minus-squaresurewhynotlem@lemmy.worldlinkfedilinkEnglisharrow-up7·2 years agoThe problem is that these mice don’t have Alzheimer’s. They’re bred to develop the symptoms: “plaques and neurofibrillary tangles, which comprise abnormally aggregated β-amyloid peptide (Aβ) and hyperphosphorylated tau protein” https://www.frontiersin.org/articles/10.3389/fnmol.2022.912995/full But that may not be what causes Alzheimer’s. That might just be an effect, and treating the effect might not fix anything.
The problem is that these mice don’t have Alzheimer’s. They’re bred to develop the symptoms: “plaques and neurofibrillary tangles, which comprise abnormally aggregated β-amyloid peptide (Aβ) and hyperphosphorylated tau protein”
https://www.frontiersin.org/articles/10.3389/fnmol.2022.912995/full
But that may not be what causes Alzheimer’s. That might just be an effect, and treating the effect might not fix anything.